Signs of Pulmonary Embolism

[unable to retrieve full-text content] Pfizer mRNA partner BioNTech reaped €19B last year but warns of lower prices in 2022    FiercePharma

There is little evidence that cough medicines work better than home remedies at easing a child's cough. Most of the time, unless a cough is causing distress or disturbing sleep, there is no need to treat it. Children's coughs usually resolve on their own after a couple of weeks. Cough medicines do not clear a cough but may make a child feel more comfortable. This article outlines current advice on treating children's coughs and home remedies that might be safer and more effective in making a coughing child feel more comfortable. There is usually no need to treat a child's cough with medication. According to the American Academy of Allergy Asthma and Immunology (AAAAI), coughing helps a child remove mucus, infections, and irritants from their respiratory tract. The AAAAI also states that most over-the-counter (OTC) cough medicines are not particularly effective. However, if a child's cough is causing distress or disturbing their sleep, caregivers may want to consult ...

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A pulmonary embolism (PE) is an obstruction in a pulmonary artery, and a saddle PE occurs when the obstruction is lodged in the main pulmonary trunk and spans the left and right pulmonary arteries. The current case study describes complications of a thrombus in transit across a patent foramen ovale (PFO). A 35-year-old female presented to the emergency department after a nontraumatic syncopal fall. She had recently returned from a cross-country flight 10 days before and had noticed left calf tenderness when exiting the plane. Vitals were notable for sinus tachycardia at 120 bpm. An electrocardiogram indicated an S1Q3T3 pattern, and chest computed tomographic angiography was positive for a saddle PE. A 2D (two-dimensional) transthoracic echocardiogram showed right ventricular free wall hypokinesis and McConnell's sign. Echocardiogram findings were concomitant with a thrombus in transit across the interatrial septum, indicating a possible PFO. An emergency pulmonary embolectomy wit...

Christine Giordano You wake up in the middle of the night with body aches and chills even though you're buried under blankets, and have a forehead that's hot to the touch. All signs point to a fever, but before you start drafting that out-of-work sick email to send to your boss in the morning, it's time to verify your suspicions by taking your temperature with one of the most valuable tools in your bathroom first-aid kit—your trusty thermometer. "Thermometers are a good tool to help assess health," says Amber Brown Keebler, MD, a physician at Nebraska Medicine. "Infections that are potentially serious are usually associated with fever." That's why it's a good idea to keep a regular eye on your body temperature. The average body temperature is 98.6 degrees, but normal body temperature can range anywhere between 97 and 99 degrees, according to the May...

With machine learning, asthma and chronic obstructive pulmonary disease (COPD) can be differentiated with moderate to high accuracy using 7 computed tomography (CT) features, according to study findings published recently in the European Respiratory Journal. Researchers sought to determine the optimal subset of CT imaging features for differentiating asthma and COPD with machine learning. To accomplish this, researchers obtained CT imaging from 47 asthma patients and 48 COPD patients recruited from the thorax clinic at Heidelberg University Hospital, Heidelberg, Germany.  Researchers then extracted and analyzed 93 features from the CT images. Differences between the asthma and COPD cohorts for age ( P =.25), BMI ( P =.31), forced expiratory volume in 1 second (FEV 1 ; P =.31), and for pulmonary function test measurements ( P >.05) were not significant. Python and MATLAB were used to implement machine learning algorithms. Researchers analyzed ...

[unable to retrieve full-text content] There are no aborted fetal cells in vaccines    Commonwealth Journal's History

Japanese-headquartered global foundry group relies on sand binder jetting from Desktop Metal's ExOne brand at facilities in Japan and the United States to deliver high-quality castings with fast turnarounds BOSTON, March 28, 2022 --(BUSINESS WIRE)--Desktop Metal, Inc. (NYSE: DM) today announced the sale of a 10 th digital sand 3D printer to the Kimura Foundry Group, a global network of foundries outfitted with cutting-edge equipment to deliver high-quality castings with increased productivity. Following the purchase of a new S-Max®, Kimura Foundry Group now owns the largest number of ExOne systems globally. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20220325005299/en/ Dr. Yoya Fukuda, President of Kimura Foundry America, with an S-Max at the company's facility in Shelbyville, Indiana. (Photo: Business Wire) ExOne, which was acquired by Desktop Metal in late 2021, is the leading digital sand printing solution provi...

Tuberculosis and COVID-19 can present with similar symptoms — get tested if you have a fever and prolonged cough March 24, 2022 — The Health Department today released a new summary of data on Tuberculosis (TB) cases in New York City (PDF) in recognition of World TB Day. New data show a 5% decrease in the number of people diagnosed with TB since 2019 [530 diagnosed with TB in 2021 compared to 566 in 2019]. In 2021, 88 percent of people with TB in NYC were born outside of the U.S. In addition, 71 percent of US-born persons with TB were non-Hispanic Black or Hispanic/Latino. Eleven percent of persons diagnosed with TB died before or during treatment. TB is the second leading infectious killer in the world, after COVID-19. According to the World Health Organization (WHO), nearly 1.5 million people died due to TB in 2020. "TB is a global health issue that has real world implications in our communities," said Health Commissioner Dr. Ashwin Vasan . "In NYC, TB diagnose...

The sudden rise in coronavirus cases has become a source of great concern. Just when we thought things were going back to normal, the BA.2 subvariant of COVID's Omicron is wreaking havoc in many parts of the world, leaving experts and doctors highly concerned. "Omicron is sweeping the world. It is the latest variant of concern and about 86% of the sequences that are available from the last four weeks are the BA.2 sub-lineage. The rest are BA.1," said Maria Van Kerkhove, the WHO's technical lead on COVID-19. The global health agency has declared the sub-lineage to be the dominant strain around the globe, which is said to be driving the current surge in Asia and Europe. Also read: Coronavirus variant: As BA.2 is on rise, know who should be more worried about BA.2 infection Prof. Tim Spector of UK's ZOE symptoms study app took to twitter to address the uptick in COVID cases in the United Kingdom. "Most cold symptoms are now Omicron infections in the U.K. as reco...

A woman in England has been diagnosed with Crimean-Congo Hemorrhagic fever according to a new report from the U.K. Health Security Agency. The viral disease is spread by ticks and livestock animals in areas of the world where it is considered endemic. These include locations in Africa, the Middle East, Asia and the Balkans and the case in the U.K. was found in a woman who had recently returned from central Asia. It is not found in ticks in the U.K. The symptoms of the disease can include fever, muscle pain, dizziness, sensitivity to light, abdominal pain and vomiting, as well as mood swings, aggression and confusion in more advanced disease. The disease is serious, with a fatality rate of up to 40% in infected individuals, but is not easily transmitted between people. Although in Spain in 2016, a man died of the disease, infecting a nurse caring from him in the process. Dr. Susan Hopkins, Chief Medical Advisor at The U.K. Health Security agency (UKHSA) said in a statement that...

Lung transplantation is a therapeutic option for end-stage lung disease, including pulmonary arterial hypertension, and has increasingly been performed following the proven success of a combined heart-lung transplant [1]. Bilateral lung transplantation (BLT) has shown to have better outcomes in pulmonary hypertension (PH) patients in terms of reduction of pulmonary arterial pressures and right heart recovery [2]. A single-center study showed a 33% prevalence of PH in bronchiectasis [3]. BLT is preferred in bronchiectasis as the residual diseased lung during a single lung transplant may result in recurrent respiratory infections and unfavorable outcomes [4]. Bronchiectasis can in severe cases cause adhesions altering the lung's architecture to the point of causing physical deviations in the structure of the mediastinum. Such changes make a BLT technically challenging and may force a single lung transplant instead of the preferred approach. A 53-year-old female with no...

A single combined-drug inhaler used as needed protects adults with mild asthma from worsening illness and hospital stays, a recent commentary on Cochrane systematic review data reports. But long-term medication and use by children under 12 years of age need to be studied, and regulatory agencies in countries including the United States have not yet approved the combined delivery. 2021 Cochrane Review Data Remain Important "The data in this review are encouraging for the use of as-needed FABA/ICS [fast-acting beta2-agonist / inhaled corticosteroid] over as-needed FABA alone for mild asthma to reduce exacerbations requiring systemic steroids, healthcare utilization and side-effects from systemic steroids," co-authors Dan Morgenstern-Kaplan, MD, and Alexei Gonzalez-Estrada, MD, of the Division of Pulmonary, Allergy, and Sleep Medicine of Mayo Clinic in Jacksonville, Florida, write in an online commentary in Clinical & Experimental ...