Coverage From the 2023 NCCN Annual Conference



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What A Blood Clot Feels Like, According To Doctors

WHEN YOU CUT YOURSELF, your blood clots over the injury to keep you from bleeding excessively. Once the injury heals, your body naturally dissolves the clot. So, blood clotting, also known as coagulation, is an important natural process.

Sometimes, however, blood clots can form in your blood vessels or arteries without an injury, and they don't naturally dissolve. When blood clots block your blood vessels and restrict blood flow, a condition known as thrombosis, it can be dangerous and even life-threatening, says Erich De Paula, M.D., associate professor of hematology at the University of Campinas in Brazil, and vice chair of the World Thrombosis Day steering committee.

"Thrombosis is responsible for about one in four deaths worldwide," he says. "This statistic should prompt the interest in learning how to avoid them through lifestyle modifications, as well as by knowing the signs and symptoms and seeking medical attention when necessary."

And they can lead to serious complications too. Blood clots can interfere with blood getting to your organs. They can affect your heart, lungs, and brain.

One of the most common types is deep vein thrombosis (DVT), when a clot forms in a deep vein in your arm or leg. The blood clots can travel to your lungs, causing a pulmonary embolism. DVT and pulmonary embolism are known as venous thromboembolism, and this affects about 900,000 Americans every year, according to the Centers for Disease Control and Prevention.

Knowing the signs of different types of blood clots, which usually revolve around pain, could help save your life, Dr. De Paula says. "Information is key, so men who are prone to thrombotic-related diseases should make informed decisions with their doctors, as to when and how to prevent thrombosis events."

What Is a Blood Clot?

Blood clots are clumps that form when platelets, proteins, and cells in your blood stick together, according to Penn Medicine. Clotting is a necessary bodily process to stop bleeding and heal an injury, and clots normally later break down and go away. When clots form where they shouldn't or not as a result of an injury, they may not break down and can cause other health problems.

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What's more, a blood clot can form anywhere in your body. It's known as deep vein thrombosis when it forms in your arm and leg veins. A pulmonary embolism develops when clots develop in your lungs. Blood clots that block blood flow to your brain can cause a stroke, and a heart attack when they form in your heart. Each type typically shows different symptoms.

Signs of a Blood Clot in Your Leg

Deep vein thrombosis (DVT) refers to blood clots that form in your body's deep veins, usually your legs or arms, according to the National Blood Clot Alliance. Symptoms might include:

  • Swelling, often in one arm or leg

  • Pain or tenderness, usually described as a cramp

  • Reddish or bluish skin

  • Leg or arm that's warm to touch

  • DjelicS - Getty Images

    "It's sometimes hard to describe," says Bibhu Mohanty, M.D., a cardiologist and associate professor of medicine at the University of South Florida. "It's like I feel pain that won't go away, but I didn't pull a muscle or hurt myself. I feel something that's tight and just hurts."

    DVT often happens after long periods of being sedentary—such as taking a long-haul flight or lengthy car trip or sitting for long periods of time, he says. Smoking, being over 60, and being overweight can increase your risk, according to the Mayo Clinic. Women who are pregnant or take birth control pills are also at a higher risk.

    You can help prevent DVT by:

  • Moving as much as possible: Get up to stretch your legs every hour or so if you're on a plane or sitting at your desk for hours

  • Quitting smoking, which increases your risk for DVT

  • Managing your weight, as being overweight increases your risk for blood clots

  • Exercising regularly, which lowers your risk for blood clots

  • Signs of a Blood Clot in Your Lungs

    When blood clots in your legs break off and travel to your lungs, it can cause a pulmonary embolism (PE). A PE is "the worst-case scenario" when you have a DVT, Dr. Mohanty says.

    ozgurcankaya - Getty Images

    Symptoms can vary depending on your overall health and the size of the blood clot, according to Penn Medicine, but as blood flow to your lungs becomes more restricted, you might experience:

  • Coughing that might produce bloody mucus

  • Dizziness

  • Heart Palpitations

  • Leg pain or swelling

  • Sudden shortness of breath

  • Sharp and sudden chest pain

  • A PE can be life-threatening, so call 911 if you experience these symptoms.

    Sometimes PE has no symptoms, however, Dr. De Paula says. In other instances, "a severe and acute PE can be experienced with symptoms from sudden death to near-fainting, severe chest pain, and abrupt shortness of breath."

    Since PE and DVT are closely related, the same groups are at risk, and moving more, managing your weight, and quitting smoking can reduce your risk for PE.

    Signs of a Blood Clot in Your Heart

    Blood clots can form in the arteries of your heart and block blood flow, causing a heart attack. Symptoms might include:

    boytaro Thongbun / 500px - Getty Images

    "It is common that patients do not point to a specific area of the chest, but rather to a more extensive and poorly defined area of the chest when asked to identify the pain point," Dr. De Paula says.

    The symptoms can occur gradually or suddenly, Dr. Mohanty says. You might also experience sweating, gas, and bloating, and it might feel like acid reflux or heartburn. Symptoms also vary depending on which artery of the heart is affected and the size of the artery.

    You can reduce your risk for a heart attack by:

  • Eating a healthy diet full of fruits, vegetables, lean protein, and whole grains, and limiting sugar and salt

  • Exercising regularly

  • Managing your weight

  • Following treatments for other health conditions

  • Signs of a Blood Clot in the Brain

    Blood clots can also block blood vessels to the brain, which can cause an ischemic stroke, the most common type of stroke.

    andreswd - Getty Images

    A stroke can happen when a blood clot forms within a blood vessel that supplies blood to the brain, known as cerebral thrombosis, according to the American Stroke Association. It can also occur when a blood clot forms in the heart or another part of your circulatory system, breaks loose, and travels through the brain's blood vessels. This is known as a cerebral embolism.

    The F.A.S.T. Warning signs can help you spot a stroke:

  • Face drooping

  • Arm weakness

  • Speech difficulty

  • Time to call 911

  • Numbness, confusion, trouble seeing, difficulty walking, and severe headaches can also signal a stroke.

    "Basically, if you're noticing a marked change in your face, your ability to talk and move your hands or arms, one compared to the other, it is extremely important to go to the hospital," Dr. Mohanty says.

    You can lower your risk for a stroke by:

    When to Seek Emergency Care

    The individual symptoms of different types of blood clots can vary, but any time you have chest pain or discomfort that's radiating to the upper limbs or neck, shortness of breath, or a cough, seek medical attention, Dr. De Paula says.

    Also, if you have unexpected pain or cramping in your leg that's not related to an injury and doesn't seem to be going away, get checked out, Dr. Mohanty says.

    Basically, any time "something isn't right and is different from your human experience, and it won't go away, it's definitely time to go in and have things looked at," he adds.

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    Tori Kelly Hospitalized: What You Need To Know About Blood Clots

    Grammy Award-winning singer Tori Kelly was hospitalized with blood clots over the weekend, ABC confirmed Tuesday.

    The singer was taken to the hospital Sunday night after collapsing while out with friends and is being treated at Cedars-Sinai in Los Angeles. She has reportedly been diagnosed with clots in her legs, also known as deep vein thrombosis, or DVT, and clots in the veins of her lungs called pulmonary emboli, or PE, according to TMZ, which was the first to report the news.

    Now, doctors are raising awareness of this life-threatening condition, saying even young people need to be aware of the signs and symptoms.

    "It absolutely can happen in young people," said ABC chief medical correspondent Dr. Jennifer Ashton.

    "This is personal for me, my daughter had one two years ago," she added. "It's a medical emergency."

    PHOTO: Tori Kelly attends special screening of Universal Pictures' "The Super Mario Bros. Movie" at Regal LA Live on April 1, 2023 in Los Angeles.

    Tori Kelly attends special screening of Universal Pictures' "The Super Mario Bros. Movie" at Regal LA Live on April 1, 2023 in Los Angeles.

    Leon Bennett/FilmMagic via Getty Images

    The symptoms of blood clots depend on their location. When a blood clot affects the deep veins of the arms or legs it can cause pain, swelling, and redness. Clots that affect the veins of the lungs can be more concerning, as they can cause shortness of breath, a fast heart rate and passing out.

    MORE: Singer Tori Kelly being treated for multiple blood clots after collapsing

    "In terms of the signs and symptoms, if you are talking about the leg, it's usually some focal tenderness or redness or swelling in the back of the leg, the calf," Ashton said. "If you're talking about a clot in the lung, it's shortness of breath, cough, chest pain that's worse [with] breathing."

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    Depending on the severity of the clots in the lungs, ICU-level care may be required.

    The Centers for Disease Control and Prevention estimates that around 900,000 people a year are affected by blood clots in the U.S. Alone. According to the CDC, approximately 25% of people with clots in their lungs experience sudden death.

    PHOTO: Tori Kelly at the Los Angeles premiere of "Fool's Paradise" held at the TCL Multiplex on May 9, 2023 in Los Angeles.

    Tori Kelly at the Los Angeles premiere of "Fool's Paradise" held at the TCL Multiplex on May 9, 2023 in Los Angeles.

    Mark Von Holden/Variety via Getty Images

    These clots can happen to anyone, but they typically occur in people who have cancer, clotting disorders, had recent surgery, are immobile, take birth control or use testosterone supplementation.

    According to the National Blood Clot Alliance, 100,000-300,000 deaths from blood clots occur annually, more significant than the number of people who lose their lives to AIDS, breast cancer and motor vehicle crashes combined.

    MORE: Artificial sweetener erythritol linked to heart attack and stroke: Study

    Doctors say the best way to prevent a blood clot from forming is by moving around as much as possible. Exercising for the recommended weekly 150 minutes of moderate-intensity physical activity and two days of muscle-strengthening training will help. Avoid sitting for more than four hours, especially on long trips. Get up and move around at least every hour whenever you travel on a plane, train or bus. Do heel-toe exercises or circle your feet if you cannot move around.

    Make sure to drink a lot of water and wear loose-fitted clothing when you travel. Speak to your doctor if you start hormone replacement medications such as birth control, estrogen or testosterone supplementation.

    If you are at a higher risk for a DVT -- including people who have recently had surgery or have a clotting disorder -- doctors recommend using compression stockings or medications that prevent blood from clotting, called anticoagulants.

    If you develop a DVT or PE, you will be treated with medicines that help your blood stop clotting. These medications work very quickly. If the drugs do not work, severe cases may involve surgery.

    Alina Mitina, D.O., is an emergency medicine resident at St. John's Riverside Hospital in Yonkers, New York, and Alexander Garcia, D.O., is an internal medicine resident at Cooper University Hospital in Camden, New Jersey. Both are members of the ABC News Medical Unit.


    DC Doctor Is First In The World To Use New Treatment For Deep Vein Thrombosis

    "One of the exciting things about this new procedure is that it allows patients who previously had no options for their blocked venous stents to have a successful procedure that can open these stents."

    Deep vein thrombosis, or DVT, is a disorder that kills an estimated 60,000 to 10,000 Americans each year.

    Dr. Steven Abramowitz, chairman of vascular surgery for MedStar Health, told WTOP that until now, vascular surgeons had few options to remove clots from venous stents placed in deep veins in the body.

    In March, Abramowitz became the first in the world to use the recently-approved RevCore thrombectomy catheter to clean out rigid clots and debris from stents in 10 patients suffering symptoms of venous stent failure at MedStar Washington Hospital Center.

    "One of the exciting things about this new procedure is that it allows patients who previously had no options for their blocked venous stents to have a successful procedure that can open these stents," Abramowitz said.

    He's also a paid consultant of Inari Medical, the company behind the RevCore device.

    Abramowitz said so far there have been no independent risks associated with the RevCore device beyond the typical risks of performing a venous based procedure such as bleeding or infection at the access site.

    He said the stent cleaning procedure is minimally invasive and is typically completed within an hour. It doesn't require a hospital stay and most patients can go back to their normal routines the next day.

    "For the most part, we've seen sustained and durable results for the patients we've intervened on thus far," said Abramowitz.

    DVT clots usually develop in the lower leg, thigh or pelvis, but they can also occur elsewhere.

    The CDC warns that symptoms can include swelling, pain, tenderness, or redness. Anyone with symptoms of DVT should reach out to their doctor as soon as possible.

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